STUDY OF CYTOTOXIC, ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF LEAVES FROM GREEN FIG TREE

نویسندگانمریم اخباری,محمد بخشی
همایشپنجمین کنگره ملی گیاهان دارویی
تاریخ برگزاری همایش۲۰۱۶-۵-۱۸
محل برگزاری همایشاصفهان
سطح همایشملی
چکیده مقالهGreen fig tree also known as common green fig is an Asian species of flowering plants in the mulberry family. It has a green edible fruit with a high nutritional value and many uses in eastern traditional medicine [1, 2]. In this study, the methanol extract from the leaves of fig tree, cultivated in Zanjan, was evaluated for its cytotoxic, antibacterial and antioxidant activity. Results confirmed that the extract has an efficient cytotoxic activity with the IC50 of 701.5 μg/ml in the brine shrimp lethality assay. Measuring antioxidant activity via DPPH bleaching assay, show high activity for the mentioned sample, compared with BHT standard antioxidant. Antimicrobial activity was evaluated using disc diffusion assay via measuring growth inhibition zoom against five important gram-positive and gram-negative bacterial strains of food-borne pathogens. Results exhibited that Escherichia coli, which is one of the most important pathogenic bacteria, is sensitive to the methanol extract of the green fig tree leaves.