Synthesis of 2,4,5-tri substituted imidazole derivatives in the presence of nano kaolin supported by Sn(IV) tetrachloride under ultrasonic conditions

Abstract

Imidazole derivatives, vital in pharmacology and industry, are efficiently synthesized using a novel nanokaolin Lewis acid catalyst supported by Sn(IV) tetrachloride. This green approach confirms high yields, rapid reactions, and versatility through ultrasonic methods and addresses concerns about solvent toxicity