A green and efficient synthesis of 1, 2, 4, 5- tetra substituted imidazoles using SbCl5/nano cellulose as catalyst

Abstract

Imidazole derivatives, five-membered heterocycles with two nitrogen atoms, have gained considerable interest for their diverse biological activities. They are fundamental components of key biomolecules like histidine and purines. These compounds have been extensively studied for their therapeutic potential against various diseases, including fungal and bacterial infections, cancer and viral infections. The synthesis of imidazole derivatives has been subjected of extensive research, with various synthetic strategies developed over the years