One-pot synthesis of 1, 2, 4, 5-tetrasubstituted imidazoles promoted by nano-TiCl4.SiO2

Authorsبی بی فاطمه میر جلیلی,عبد الحمید بامنیری,لیلا زمانی
Journalscientia iranica
Page number565
Volume number19
IFثبت نشده
Paper TypeFull Paper
Published At2011-12-17
Journal GradeScientific - research
Journal TypeElectronic
Journal CountryIran, Islamic Republic Of
Journal IndexSCOPUS ,ISC ,JCR

Abstract

Nano-TiCl4.SiO2 is an efficient, readily available and reusable catalyst for the synthesis of 1, 2, 4, 5-tetrasubstituted imidazoles using benzil, aromatic aldehyde and an amine in the presence of ammonium acetate. The one-pot procedure is very simple with good to excellent yields.

tags: 1, 2, 4, 5-tetrasubstituted imidazoles; Nano-TiCl4.SiO2; Benzil; One-pot synthesis; Solvent free condition; Supported Lewis acid.