Bio-Based Hybrid Catalysts for the Synthesis of Pharmacologically Active Xanthenes

Abstract

We synthesized an efficient bio-based nano-catalyst, – Fe3O4@nano linear dextrin/Sb+5 (Fe3O4@NLD/Sb+5) – from nano linear dextrin and antimony pentachloride via straightforward steps. The nano-catalyst was used to synthesize solvent-free 14-aryl-14H- dibenzo[a, j]xanthene derivatives based on 2- aminobenzimide and different aldehydes. The synthesized nano-catalyst bears many critical advantages: nontoxicity, biocompatibility, affordability, easy work-up method, environmentally friendliness, and high yields, as well as being solventfree and operable under green conditions.