Fabrication of LSPR sensor chip with immobilization of Au nanoparticles on the transparent substrate

Abstract

: Nanoparticles of noble metals are well known to display unique optical properties due to the localized surface plasmon resonance (LSPR) phenomenon, for this reason use as transducers in various LSPR sensor configurations. In order to develop a sensor chip, Au nanoparticles (AuNPs) were decorated onto a transparent substrate in the form of a uniform and high-density single layer using a self-assembly monolayer (SAM) process. The glass substrate surface was modified with amine functional groups via different concentration of (3-Aminopropyl) triethoxysilane (APTES) then were optimized to control AuNPs monolayer uniformly. The optimized plasmonically substrate was subsequently prepared by dipping into AuNPs solution for 1 h and overnight (%0.5 APTES – 1 h). Moreover, using the finite-difference time-domain (FDTD) to describing of LSPR, 3D Au nanoparticles on a glass substrate were simulated.