Synthesis of orthoaminocarbonitrile tetrahydronaphthalenes catalyzed by butyl-3- methylimidazolium hexafluorophosphate ionic liquid base catalyst

Abstract

In this research, the treatment of cyclohexanone, malononitrile, and aromatic aldehydes was carried out for the successful synthesis of orthoaminocarbonitrile tetrahydronaphthalenes by using butyl-3- methylimidazolium hexafluorophosphate as a base catalyst. In this protocol, the target products were obtained in high to excellent yields between 85% and 95% and short reaction times between 10 and 20 min under mild conditions. All products were identified by the melting points, FT-IR, and 1 H NMR techniques.