Microwave-promoted total synthesis of N-(α-hydroxybenzyl)formamides using DMSO/H2O under neutral conditions

Authorsخدیجه ربیعی,حسین نعیمی
JournalGREEN CHEM LETT REV
Page number44
Volume number9
IF0.512
Paper TypeFull Paper
Published At2016-08-11
Journal GradeScientific - research
Journal TypeElectronic
Journal CountryIran, Islamic Republic Of
Journal IndexISI ,SCOPUS

Abstract

A total synthesis route toward N-(α-hydroxybenzyl)formamides by microwave-assisted reaction of dichloroaziridines and aqueous dimethyl sulfoxide is described. The corresponding products were obtained in excellent yields with reduced reaction times. The obtained formamides were characterized by various techniques such as Infra red (IR), Nuclear Magnetic Resonance (NMR) and mass spectroscopy data.

tags: Formamide, aziridine, microwave, dimethyl sulfoxide, synthesis