Rapid One Pot Synthesis of Benzoimidazoles Using MnO2 Nanoparticles Supported on Silica as Efficient Oxidant Agent under Solvent-Free Conditions

Abstract

A novel one-pot and mild synthesis of benzoimidazole derivatives through the reaction of o-Phenylenediamine with aromatic aldehydes in the presence of MnO2 nanoparticles supported on silica as oxidizing agent under grinding conditions. The significant features of the present protocol are; simplicity of procedure, high products yields, purity of products, solvent-free condition, and easily work-up procedure.