Nanocrystalline magnesium oxide: an efficient promoter and heterogeneous nano catalyst for the one-pot synthesis of pyrazolotriazoles in green medium

Authorsحسین نعیمی,زهرا رشید,امیر حسن زرنانی,رامین قهرمان زاده
JournalJ NANOPART RES
Page number1
Volume number16
IF2.184
Paper TypeFull Paper
Published At2014-04-11
Journal GradeScientific - research
Journal TypeElectronic
Journal CountryIran, Islamic Republic Of
Journal IndexISI ,SCOPUS

Abstract

A simple, efficient, and relatively clean method for the synthesis of pyrazolo[1,2-a][1,2,4]triazole derivatives via a one-pot three-component reaction of aromatic aldehydes, 4-phenyl-1,2,4-triazolidine-3,5-dione, and malononitrile or alkyl cyanoacetates in the presence of a catalytic amount of nanocrystalline (NC) magnesium oxide has been developed. This method has several advantages such as, high to excellent product yields, reusability of catalyst, and simple work-up procedure in the nontoxic medium.

tags: Multi-component reaction Green medium Magnesium oxide Pyrazolotriazoles 4-Phenyl-1,2,4-triazolidine-3,5-dione Malononitrile Benzaldeyde