Serine proteases and their role in cancer cell metastasis

Abstract

Serine proteases are a diverse group of enzymes crucial in regulating various physiological functions. They can suppress inflammatory responses and promote tissue regrowth. These enzymes also involve the complex interplay between the tumor environment and cancer cell growth. This study aims to investigate the multifaceted roles of serine proteases in cancer, shedding light on how they can both promote and inhibit tumor growth. The research explores how these enzymes facilitate processes such as angiogenesis, tumor aggression, and metastasis, which makes them potential targets for cancer treatment. The study also addresses the challenges associated with developing effective therapies, focusing on strategies that involve modulating serine protease activity. Furthermore, the review discusses novel approaches for utilizing serine proteases in cancer diagnosis and treatment, highlighting their potential as valuable therapeutic targets. This comprehensive overview emphasizes the intricate relationship between serine proteases and cancer, demonstrating their capacity to contribute to disease progression while also serving as promising therapeutic targets.