Fabrication, characterization, antibacterial properties, and the possibility of introducing silver tungstate nanoparticles with Zn as photosensitizers for photodynamic therapy

Abstract

This study aims to investigate the behavior of Ag1.8Zn0.1WO4 nanoparticles in the production of singlet oxygen and hydroxyl free radicals to improve photodynamic therapy. Anthracene and methylene blue reagents were used as detectors for this purpose. First, Ag1.8Zn0.1WO4 nanoparticles were produced using the chemical method. Then their structural characteristics and nature were examined by X-ray diffraction (XRD), Scanning Electron Microscopy (SEM), and Energy Dispersive Spec- troscopy (EDS). The optical properties of synthesized nanoparticles were investigated by photoluminescence spectroscopy. By excitation at wavelengths of 300 and 480 nm, emission peaks were observed at wavelengths 380, 430, and 460 nm. And then, the antibacterial properties of the nanoparticles produced were studied by two methods. It was shown that the prepared nanoparticles had effective antimicrobial activity against bacteria. Therefore, due to the excellent photodynamic and anti- bacterial properties of these nanoparticles, they can be used as an effective drug for treatment.