Application of linear multivariate calibration techniques in assessment of the peaks responsible for antimicrobial activity of Oliveria decumbens Vent. using gas chromatography-mass spectrometry technique

چکیده مقاله

Oliveria decumbens Vent. is known for their diverse effects in drugtherapy and traditional medicine. In this study, essential oil of aerial parts of Oliveria decumbens Vent. from different regions was obtained by hydrodistillation and was analyzed by gas chromatography-mass spectrometry (GC-MS) and its antimicrobial activities against three microbial strains were evaluated by disc diffusion method and micro-broth dilution assay. The peaks potentially responsible for the antimicrobial activity in essential oils samples were identified by numerous linear multivariate calibration techniques. The best performance in indicating the potential antimicrobial compounds in Oliveria decumbens Vent essential oils was obtained by independent component regression (ICR), because of its simplicity and interpretability of the regression coefficients.