Assessment of the peaks responsible for antimicrobial activity of Satureja hortensis L. essential oil using gas chromatography-mass spectrometry technique

چکیده مقاله

Satureja hortensis L. is used in traditional medicine in the world due to its antifungal, antibacterial and antioxidant properties. In this study, the antimicrobial activities in Satureja hortensis L. essential oils against three microbial strains were evaluated by two different methods, including: disc diffusion method, micro-broth dilution assay and qualitative analysis was performed by gas chromatography-mass spectrometry technique. The peaks potentially responsible for the antimicrobial activity in essential oils samples were indicated by some linear multivariate calibration techniques with different preprocessing methods. From the studied techniques, independent component regression (ICR) was preferred to exhibit the potential antimicrobial active compounds in Satureja hortensis L. essential oils because of its high repeatability, simplicity and interpretability of the regression coefficients.