Determination of Very Low Level of Free Formaldehyde in Liquid Detergents and Cosmetic Products Using Photoluminescence Method

چکیده مقاله

Formaldehyde is commonly used in detergents and cosmetic products as antibacterial agent and preservative. Ths substance is unfavorable for human health because it is known to be toxic for humans and causes irritation of eyes and skins. Th toxicology studies of this compound indicate risk of detergents and cosmetic formulations with a minimum content of 0.05% free formaldehyde. Threfore, determination of formaldehyde as quality control parameter is very important. In this study, a photoluminescence method was achieved by using 2-methyl acetoacetanilide. Also, the Box-Behnken design was applied for optimization of Hantzsch reaction for formaldehyde derivatization. Th investigated factors (variables) were temperature, % v/v ethanol, reaction time, ammonium acetate, and 2-methyl acetoacetanilide concentration. Th linear range was obtained from 0.33– 20 × 10−7 M (1–60