Efficient One-Pot Synthesis of 1,4-Dihydropyridines Catalyzed by Magnetic MnFe2O4 Nanoparticles

AuthorsS Moradi, M Moradian, H Naeimi
JournalActa Chim. Slov
Page number349
Volume number69
IF1.524
Paper TypeFull Paper
Published At2022-03-16
Journal GradeScientific - research
Journal TypeElectronic
Journal CountryIran, Islamic Republic Of
Journal IndexJCR

Abstract

The efficient one-pot synthesis of some 1,4-dihydropyridines is described by a condensation reaction of some aldehyde derivatives, ethyl acetoacetate and ammonium acetate in the presence of superparamagnetic manganese ferrite nanoparticles at 80 °C. The advantages of this protocol include selectivity, high purity of the products, excellent yields, short reaction times, ease of processing, and environmentally friendly conditions for the synthesis of 1,4-dihydropyridines. In addition, the catalyst can be recovered and reused in multiple runs without significantly reducing the product yield.

tags: 1,4-Dihydropyridine; MnFe2O4; Nanoparticles; Catalyst; Superparamagnetism