| Authors | عباس جعفری کاشی,مهدی شبانی نوش آبادی |
|---|
| Journal | Analytical & Bioanalytical Electrochemistry |
|---|
| Page number | 1016 |
|---|
| Volume number | 10 |
|---|
| Paper Type | Full Paper |
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| Published At | 2018-10-11 |
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| Journal Grade | Scientific - research |
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| Journal Type | Electronic |
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| Journal Country | Iran, Islamic Republic Of |
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| Journal Index | SCOPUS ,ISC |
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Abstract
A sensor based on carbon paste electrode (CPE) modified with benzoylferrocene
(BF) and NiO nanoparticls (NiO/NPs) was used for the highly sensitive voltammetric and
electrocatalytic measurement of hydrochlorothiazide (HCT) and folic acid (FA). The
NiO/NPs were synthesized via a direct chemical precipitation method and were characterized
with X-ray diffraction (XRD), and scanning electron microscopy (SEM) techniques. The
obtained sensor represented a suitable and powerful electron mediating behavior along with
excellent-separated oxidation peaks of HCT and FA. The acquired peak currents from square
wave voltammetry (SWV) technique were linearly dependent on HCT and FA concentrations
in the ranges of 1.0–500.0 and 50.0–500.0 µmolL
-1
with limits of detection equal to 0.14 and
4.3 µmolL
-1
, respectively. This mediator/nanoparticle modified electrode was applied for the
detection and measurement of HCT and FA in pharmaceutical and biological samples.
