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Roohallah Nakhaei Sistani

Roohallah Nakhaei Sistani

Assistant Professor

College: Faculty of Chemistry

Department: Cell and Molecular Biology

Degree: Ph.D

Birth Year: 1979

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Roohallah Nakhaei Sistani

Assistant Professor Roohallah Nakhaei Sistani

College: Faculty of Chemistry - Department: Cell and Molecular Biology Degree: Ph.D | Birth Year: 1979 |

Assistant Professor

Molecular Genetics, University of Kashan, Kashan, Iran, 2013-Now

Field of interest: Biology of morphine addiction, miRNAs, Cancer biology, Herbal medicine, Bioinformatics. MicroRNAs are small RNA molecules which regulate many biological processes, including development, cancer, and also
addiction. And Bioinformatics, in my opinion, is a tool to explain many aspects of molecular biology, and unraveling neglected data, especially mass data. Iran has a great history of medicine based on herbs and working on herbs is promising for incurable diseases.

Ph.D

Molecular Genetics, Tarbiat Modares University, Tehran, Iran, 2008-2013.

During my Ph.D., I was working on microRNAs involving in morphine response in BE-2-C neuronal cell line as a model for molecular events happening in cells in the process of opioid addiction. Our data analysis indicates many biological pathways which could be involved in this process.

Master of Science

Molecular Genetics, Tarbiat Modares University, Tehran, Iran, 2002-2005.

Have you ever heard about DIAPOPS. This is a PCR-based technique which does not need for agarose gel electrophoresis. It uses a probe and enzymatic reaction for visualizing PCR products. I used this technique to detect fastidious adenoviruses in stool samples in my Ms.c.

Bachelor of Science

Plant Biology, Ferdowsi University, Mashhad, Iran, 1997-2002.

نمایش بیشتر

Prevalence and Risk Factors of Hepatitis B among Blood Donors in Al-Najaf Governorate

Authorsمهدی عبود,روح اله نخعی سیستانی,موسی نیما مژر الجعیفری,علا عبدالحسین رسول,هاشم علی عبداعامر الشریس
JournalBiosciences Biotechnology Research Asia
Page number133
Volume number17
Paper TypeFull Paper
Published At2020-04-10
Journal GradeScientific - research
Journal TypeElectronic
Journal CountryIran, Islamic Republic Of
Journal IndexSCOPUS

Abstract

Hepatitis B virus (HBV) infection is a global problem. When the virus replicates in the hepatocytes, the liver functions will be impairedand the infection will spread throughout the liver. Blood and blood products contain HBV, and therefore the virus could be transmitted via blood transfusion. The aim of this study was to investigate the prevalence of viral hepatitis B (HBsAg and anti-HBc antibody) among the blood donors of the main blood bank in AL-Najaf governorate (central Iraq). We also analyzed some factors which may be associated with HBV infection. To do this, a total of 16273 blood samples were collected from voluntary donors from (20/5/2016) to (12/12/2016). The presence of HBV was tested by enzyme-linked immunosorbent assay (ELISA) for HBsAg and anti-HBc antibody. The samples were also analyzed in part for age range, gender, profession, liver enzymes and blood characterization. Our results showed that 41 individuals were chronically infected with HBV, one of them was female. Most of the infected patients were aged between 28-37 years old (47.6%). It is showed that HBV infected people have significantly higher levels of Serum Glutamic-Oxaloacetic Transaminase (SGOT) and Serum glutamic pyruvic transaminase (SGPT) compared with the control (P < 0.001 and P <0.011 respectively). The increased levels were also observed for lymphocytes and platelets (P<0.055 and P<0.429 respectively). The results also showed that the virus is more distributed between drivers (33.3%).