Synthesis of Polyhydroquinoline Derivatives Using Fe3O4@polyethyleneglycol (PEG) Core/Shell

Abstract

In current study, magnetite nanoparticles supported with a PEG were first synthesized and applied in asymmetric hantzsch reactions for preparing polyhydroquinoline derivatives with high efficiencies. The MNPs both promote the reaction rate and simplify the work-up procedure. Furthermore, the nanomagnetic catalyst could be recovered from solution with an external magnet at once, allowing undemanding recovery and reuse. In addition, the catalyst was reused for five times with no considerable decrease in catalytic activity. Short-time reaction, excellent efficiency of the products, simple operation, and environmental friendly process are other highlights of this new catalyst.