Sonosynthesis of Thiazolidinones Using Nano-Fe3O4-tethered Polyhedral Oligomeric Silsesquioxanes with Eight Branches of 3-Aminopropyltriethoxysilane

Abstract

An effective way for the synthesis of bis-thiazolidinones was applied by one-pot pseudo-five-component reaction of benzaldehydes, ethylenediamine, 2-mercaptoacetic acid with nano-Fe3O4-tethered polyhedral oligomeric silsesquioxanes with eight branches as catalyst under ultrasonic conditions. The catalyst was characterized by Fourier-transform infrared spectroscopy, scanning electron microscope, X-ray diffraction, energy-dispersive X-ray spectroscopy, Brunauer-Emmett-Teller, thermogravimetric analysis, and vibrating-sample magnetometer. The remarkable advantages of this methodology are easy work-up, short reaction times, high to excellent product yields, low catalyst loading and reusability of the catalyst.