AfterglowpropertiesofCaF2:Tm nanoparticlesanditspotential application inphotodynamictherapy

AuthorsM. Zahedifar- E.Sadeghi - M.M.Shanei - A.Sazgarnia - M.Mehrabi
JournalJournal ofLuminescence
Paper TypeFull Paper
Published At3December2015
Journal GradeISI
Journal TypeTypographic
Journal CountryIran, Islamic Republic Of

Abstract

CaF2:Tm nanoparticles(NPs)weresynthesizedbythehydrothermalmethod.Intenseafterglowemission
with longlifetimewasfoundfortheproducedNPs,soitsapplicabilityinphotodynamictherapywas investigated.SincethewavelengthoftheafterglowemissionoftheNPsfairlymatcheswiththe
absorption bandofthePpIXsensitizer,especiallyintheredregion,theCysteinmediatorwasusedto
bond NPswiththePpIXsensitizer.TheCaF2:Tm NPsconjugatedwithPpIXwasexposedtoX-rayandby
using theAntraceneasdetector,theproductionofthesingletoxygenwasverified. Therefore,thepro-
duced NPsarerecommendedasasourceofenergythatimprovesphotodynamictherapybeyondits
current limitations.

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