The anticancer effects of different species of Cynanchum

Abstract

The prevalence of cancer is increasing worldwide. Oxidative stress and chronic inflammation or disturbance in signaling and metabolism lead to an increase in diseases such as cancer, diabetes, and cardiovascular diseases. Oxidative stress caused by excessive production of free radicals and reactive oxygen species (ROS) disrupts cell function, including general changes in the cellular system, followed by the development of cancerous tumors. Today, many drugs and chemical methods have been discovered for cancer. However, no effect of plant compounds in the treatment and prevention of cancer can be ignored. In this review article, we will examine several cynanchum plant species and their action mechanism as anticancer drugs.