Encapsulation of Thiosalen Complex in NaY Nanoporosity: An Efficient Catalyst For Asymmetric A3-Coupling Reaction

چکیده مقاله

The development of new enantiopure ligands that provide a chiral environment around metals so that they perform efficient asymmetric synthesis is one of the most straightforward challenges for organic chemists [1]. In addition, due to the high coordination ability of the sulfur atom to most transition metals [2], asymmetric sulfur ligands have also been developed for enantioselective catalysis in the last 20 years [3]. The sulfur atom is considered as a soft atom and forms strong bonds with soft metals. Nanodimensional microreactor containing (1R,2R)-N,N-bis[2-(phenylthio) benzylidene] 1,2-diaminocyclohexane copper(I) bromide, [Cu(AsN2S2)]Br@Y have been successfully prepared. This nano composite used as a asymmetric catalyst in one-pot multicomponent coupling reaction of aldehydes, amines and alkynes toward synthesis of propargylamines. The copper (I) complex with N2S2 donor Schiff base ligand was readily trapped in the nanocavity of zeolite-Y through a template synthesis method (TS).