A Practical One-Pot Electrochemical Synthesis of Pyrimido[4,5-b]indole Derivatives

نویسندگانM Shabani-Nooshabadi, M Moradian, S Dadkhah-Tehrani
نشریهB CHEM SOC JPN
شماره صفحات68
شماره مجلد90
ضریب تاثیر (IF)1.372
نوع مقالهFull Paper
تاریخ انتشار2017-01-11
رتبه نشریهعلمی - پژوهشی
نوع نشریهالکترونیکی
کشور محل چاپایران
نمایه نشریهISI ,SCOPUS

چکیده مقاله

In the present work, electrochemical synthesis of novel pyrimido[4,5-b]indoles was directly carried out via the electrochemical oxidation of catechols in the presence of 2,4-diamino-6-hydroxypyrimidine in an aqueous media. The results suggested that electrogenerated o-benzoquinone moieties participated in the Michael-type addition reaction with 2,4-diamino-6-hydroxypyrimidine via the ECEC mechanism. These new compounds were synthesized in high yields and purity in an aqueous solution without toxic reagents or catalyst and with high atom economy in ambient conditions.

tags: Electrochemical, Synthesis, Pyrimido[4,5-b]indole, green media