Synthesis Of Bis-spiropiperidines Using Nano-CuFe۲O۴@ Chitosan As A Robust And Retrievable Heterogeneous Catalyst

چکیده مقاله

An efficient pseudo six-component synthesis of bis-spiropiperidines is described by one-pot condensation of formaldehyde, aromatic amine and dimedone or N,N-dimethyl-barbituric acid using nano-CuFe2O4@chitosan at room temperature. This method provides several advantages including mild reaction conditions, applicability to wide range of substrates, reusability of the catalyst and little catalyst loading.