A Direct Palladium-Catalyzed Route for the Synthesis of Benzo[a]carbazoles: Synthesis and Photophysical Properties of Diverse Benzo[a]carbazoles

چکیده مقاله

Aryl- and heteroaryl-annulated carbazoles play an essential role in various areas of synthetic and medicinal chemistry that have been comprehensively reviewed, they are particularly noted for their diverse biological and pharmacological activities. A direct, concise, and atom-economical synthetic method for the generation of benzo[a]carbazoles, using a palladium-catalyzed reaction has been developed. The reaction produces gave various benzo[a]carbazoles in good to excellent yields, through Knoevenagel condensation followed by intramolecular ortho-arylation. The synthetically attractive feature of the procedure is reflected by its applicability to a wide range of indole and bromobenzaldehyde derivatives.