Assistant Professor
College: Faculty of Chemistry
Department: Cell and Molecular Biology
Degree: Ph.D
Birth Year: 1979
Assistant Professor
Molecular Genetics, University of Kashan, Kashan, Iran, 2013-Now
Field of interest: Biology of morphine addiction, miRNAs, Cancer biology, Herbal medicine, Bioinformatics. MicroRNAs are small RNA molecules which regulate many biological processes, including development, cancer, and also
addiction. And Bioinformatics, in my opinion, is a tool to explain many aspects of molecular biology, and unraveling neglected data, especially mass data. Iran has a great history of medicine based on herbs and working on herbs is promising for incurable diseases.
Ph.D
Molecular Genetics, Tarbiat Modares University, Tehran, Iran, 2008-2013.
During my Ph.D., I was working on microRNAs involving in morphine response in BE-2-C neuronal cell line as a model for molecular events happening in cells in the process of opioid addiction. Our data analysis indicates many biological pathways which could be involved in this process.
Master of Science
Molecular Genetics, Tarbiat Modares University, Tehran, Iran, 2002-2005.
Have you ever heard about DIAPOPS. This is a PCR-based technique which does not need for agarose gel electrophoresis. It uses a probe and enzymatic reaction for visualizing PCR products. I used this technique to detect fastidious adenoviruses in stool samples in my Ms.c.
Bachelor of Science
Plant Biology, Ferdowsi University, Mashhad, Iran, 1997-2002.
| # | Paper Title | Authors | Publication/Conference | Date | Type |
|---|---|---|---|---|---|
| 1 | E-Cadherin/β-Catenin Complex: A Target for Anticancer and Antimetastasis Plants/Plant-derived Compounds | Majid Tafrihi- Roohollah Nakhaei Sistani | Nutrition and Cancer | 2017 | Article In Publication |
| 2 | The designation of PCR test to detect hepatitis B virus and evaluate the performance of this test in screening applicants of blood transfusion organization | Roohollah Nakhaei Sistani- Seyed Mahdi Sadatolhosseini | Journal of Cellular and Molecular Researches | 2017 | Article In Publication |
| 3 | Analysis of long-term treatment of Mu opioid receptors agonists effect on Dnm1L and Rab22a expression in HEK293 Flp-In MOP YFP | Sheida Ilkhanizadeh- Roohollah Nakhaei Sistani- Majid Sadeghizadeh- Ghasem Ahangari | Pathobiology research | 2017 | Article In Publication |
| 4 | Identifying microRNAs relating to morphine response in BE (2)-C cell line by microRNA profiling | Roohollah Nakhaei Sistani- Majid Sadeghizadeh- Bahram Mohammad Soltani | Proceedings of the National Academy of Sciences, India Section B: Biological Sciences | 2017 | Article In Publication |
| 5 | MicroRNAs Signature in IL-2-Induced CD4+ T Cells and Their Potential Targets | Najmeh Ranji- Majid Sadeghizadeh-Morteza Karimipoor-Mohammad Ali Shokrgozar-Roohollah Nakhaei Sistani-Seyed Hasan Paylakhi | Biochemical genetics | 2015 | Article In Publication |
| 6 | Effect of acetone-derived pomegranate extract on the expression of E-cadherin and β-catenin proteins in PC-3 cells | Majid Tafrihi- Roohollah Nakhaei Sistani | Journal of Cellular and Molecular Researches | 2015 | Article In Publication |
| 7 | Evaluation of apoptosis induction on gastric cancer AGS cells made by polymer Nano curcumin | Alireza Panahi- Roohollah Nakhaei Sistani- Majid Sadeghizadeh | Police medicine | 2014 | Article In Publication |
| 8 | Analysis of the Effect of Chronic Morphine Treatment on miRNA Profile and Introduction of the MAPK Pathway as the Target of Differentially Expressed miRNAs | Roohollah Nakhaei Sistani- Majid Sadeghizadeh- Bahram Mohammad Soltani | Pathobiology resaerch | 2013 | Article In Publication |
| 9 | Inverted metabolic engineering of E. coli toproduce PHB and simplifying of lysis process, using gene E from phage PhiX174 | Roohollah Nakhaei Sistani- Hadi Shirzad- Mojtaba Saadati | Journal of Army University | 2010 | Article In Publication |
| 10 | A Genetic-epidemiological Case-control Study of HLA-DQB1*05and Multiple Sclerosis in Tehran | فاطمه خبیری,روح اله نخعی سیستانی | Journal of Genetic Resources | 2025-09-23 | Article In Publication |
| 11 | HLA-DQB1*06 May Predispose People to Multiple Sclerosis (MS) | نفیسه خلیلی,روح اله نخعی سیستانی,هادی شیرزاد | Biomacromolecular Journal | 2024-05-08 | Article In Publication |
| 12 | Association between PON1-rs662 Gene Polymorphism and Diabetic Retinopathy in Population of the Qom, Iran | فاطمه صباغیان بیدگلی,اباصلت حسین زاده کلاگر,مجید تفریحی,روح اله نخعی سیستانی | Avicenna Journal of Medical Biotechnology | 2023-09-13 | Article In Publication |
| 13 | Screening rs2241766 Polymorphism as a Susceptibility Index Parameter in Obese Patients with a High Level of Cholesterol | نگار ربیعی فرادنبه,روح اله نخعی سیستانی,علی محمد احدی | Journal of Genetic Resources (J Genet Resour) | 2022-08-23 | Article In Publication |
| 14 | HLA-DQB1*06 May Predispose People to Multiple Sclerosis (MS) | نفیسه خلیلی,روح اله نخعی سیستانی,هادی شیرزاد | Biomacromolecular Journal | 2022-07-08 | Article In Publication |
| 15 | EVALUATION OF THE CORRELATION BETWEEN SERUM LIPID CHARACTERISTICS OF OBESE SUBJECTS AND ADIPOQ GENE RS266729 POLYMORPHISM IN CHAHARMAHAL AND BAKHTIARI PROVINCE OF IRAN | نگار ربیعی فرادنبه,روح اله نخعی سیستانی,علی محمد احدی,رضا بهارلو | Journal of Current Biomedical Reports | 2020-12-08 | Article In Publication |
| 16 | Prevalence and Risk Factors of Hepatitis B among Blood Donors in Al-Najaf Governorate | مهدی عبود,روح اله نخعی سیستانی,موسی نیما مژر الجعیفری,علا عبدالحسین رسول,هاشم علی عبداعامر الشریس | Biosciences Biotechnology Research Asia | 2020-04-10 | Article In Publication |
| 17 | Studies on combination of oxaliplatin and dendrosomal nanocurcumin on proliferation, apoptosis induction, and long non-coding RNA expression in ovarian cancer cells | Seyed Hosseini E - Alizadeh Zarei M - Babashah S - Nakhaei Sistani R - Sadeghizadeh M - Haddad Kashani H - Amini Mahabadi J - Izadpanah F - Atlasi MA - Nikzad H | Cell Biology and Toxicology | 2018/11/28 | Article In Publication |
| 18 | Studies on combination of oxaliplatin and dendrosomal nanocurcumin on proliferation, apoptosis induction, and long non-coding RNA expression in ovarian cancer cells | الهه سید حسینی,مرضیه علیزاده زایری,صادق باباشاه,روح اله نخعی سیستانی,مجید صادقی زاده,حامد حداد کاشانی,جواد امینی مهابادی,فاطمه ایزدپناه,محمدعلی اطلسی,حسین نیکزاد | CELL BIOL TOXICOL | 2018-11-11 | Article In Publication |
| 19 | The study of the prevalence of hepatitis G virus among clients referring to Kashan Blood Transfusion Organization | Roohollah Nakhaei Sistani- Seyed Mahdi Sadatolhosseini | 3rd National conference on modern biologicalscience and technology | 2017/5/11 | Article In Conference |
| 20 | Designing a PCR-based system to identify the HLA-DQB1 * 03 allele in a sample population from Tehran | Roohollah Nakhaei Sistani- Marzieh Salehi Siavashani | 3rd National conference on modern biologicalscience and technology | 2017/5/11 | Article In Conference |