Synthesis of pyridine derivatives via using magnetic nanocatalyst Fe۳O۴@SiO۲@SO۳H as a reusable catalyst

چکیده مقاله

Pyridines represent a common scaffold in numerous bioactive compounds and have a number of pharmacological properties 1,2 2-amino-3-cyanopyridine derivatives are synthesized from aldehydes, ketones, malononitrile, and ammonium acetate catalyzed by Sulfonic acid-functionalized silica-coated nano-Fe3O4 particles (Fe3O4@SiO2@SO3H) (Scheme 1). This procedure has high yields، easy workup and reusability nanocatalyst.