Green sol–gel auto-combustion synthesis, characterization and study of cytotoxicity and anticancer activity of ErFeO3/Fe3O4/rGO nanocomposite

Abstract

Due to the fact that researchers and scientists have been interested in environmentally friendly synthesis using plant extracts because of the wide distribution of plants, their ease of availability, and their safety in use, in the current work, ErFeO3/Fe3O4/rGO nanocomposite was produced using a green chemistry method via sucrose indicating the importance of both an active capping and reducing agent for the synthesis of nanocomposite materials with well-organized biological properties. Number of methods, including TEM, SEM, XRD, BET-BJH, VSM, and HRTEM, were used to characterize the produced nanocomposite. The XRD data showed that the produced nanocomposite had pure particles with a range of 37 ± 2 nm in size, which was validated by TEM examination. Additionally, the nanocomposite’s cytotoxicity was examined to test its anti-proliferative effect against the T98, and SH-SY5Y cancer cell lines. It was also discussed how to effectively induce cancer cell death in vitro when manufactured nanocomposite was present. The results showed that the percentage of cells that survived was drastically decreased by the synthesized nanocomposite. However, further research must be done to identify the precise linked mechanisms.