Facile and efficient sonochemical synthesis of 1,4-disubstituted 1,2,3-triazole derivatives catalyzed by CuI under mild conditions

نویسندگانحسین نعیمی,سمیرا داداش زاده مهماندوست ,محسن مرادیان
شماره صفحات2687
شماره مجلد41
ضریب تاثیر (IF)1.221
نوع مقالهFull Paper
تاریخ انتشار2015-06-11
رتبه نشریهعلمی - پژوهشی
نوع نشریهالکترونیکی
کشور محل چاپایران
نمایه نشریهISI ,SCOPUS

چکیده مقاله

A facile and highly efficient method for regioselective synthesis of 1,4-disubstituted 1,2,3-triazoles in good to excellent yields from in-situ-generated azides and terminal alkynes by Cu(I)-catalyzed 1,3 dipolar cycloaddition (the so-called click reaction), is described. The reaction proceeds smoothly in a 1:1 mixture of water and ethanol at room temperature without any additive. The method is a convenient means of preparation of a wide range of triazoles in a one-pot operation via a three-component reaction.

tags: Synthesis 1,2,3-Triazole Ultrasound Catalyst Click chemistry 1,3-Dipolar cycloaddition