Extract From Mentha Longifolia As Natural Antimicrobial.

چکیده مقاله

Background: Mentha longifolia is a species in the genus Mentha (mint) native to Europe, western and central Asia (east to Nepal and the far west of China), and northern and southern (but not tropical) Africa. Methods: This plant was collected in August 2016 from southwest of Marivan. Extractions methanol were performed with a Soxhlet apparatus. The extract was concentrated using a rotary evaporator. The antimicrobial activity of the sample was examined against a set of twelve microorganisms. The samples investigated for antimicrobial activity by agar well diffusion method.The microbial strains sensitive to the plant in disc diffusion assay were studied for their minimal inhibitory concentration (MIC) values using micro-well dilution assay method. Gentamicin and Rifampin were examined as positive controls and DMSO as negative control. Results: The results showed that the sample had antimicrobial activity against p. aeruginosa, S. epidermidis, B. subtilis and A. brasilienis. The inhibition zone diameter for the sample was between 11-21 mm. The samples exhibited activity against the tested microorganisms with MIC 31.25 μg/ml. Conclusion: Results of present study indicated that extract of Mentha longifolia had significant antimicrobial activity. These studies suggest that Mentha longifolia may be a promising source for novel antimicrobial agents.