Solid phase synthesis of linear peptide Longicalycinin A analogues by using 2-chlorotrityl chloride resin

چکیده مقاله

The aim of this study is designing of linear penta peptide Longicalycinin A analogues which might have expected anticancer activity. In this work, linear penta peptide Longicalycinin A and their two analogues, which have shown good toxicity against cell lines of HepG2 (human liver cancer cell line), HT-29 (human colorectal adenocarcinoma cell line) and A549 (adenocarcinomic human alveolar basal epithelial cells) using MTT assay.